A quick and reliable way to induce emesis.

Clevor is a selective emetic with a fast onset of action and a short duration of vomiting — making emesis induction quicker and less stressful.1,2

The active ingredient in Clevor is ropinirole, which is a full dopamine agonist with selectivity for dopamine D2-type receptors.2

Ropinirole mediates induction of emesis very readily in dogs by stimulating these receptors in the chemoreceptor trigger zone (CRTZ) in the brain stem.1

Unlike other emetic options,
Clevor does not need to be:

  • Requested from a compounding pharmacy
  • Resuspended or crushed to be administered
  • Flushed from the eye after administration

Proven safety and efficacy.

The efficacy and safety of Clevor were assessed in a randomized, double-blind, placebo-controlled clinical field study with 100 dogs in the Clevor group.1

vomited after a
single dose2

51%

Median time to first vomit was 12 minutes
(range: 3 to 37 minutes)2

95%

vomited within
30 minutes1

90%

stopped vomiting within
45 minutes2

CLEVOR® is indicated for the induction of vomiting in dogs.

IMPORTANT SAFETY INFORMATION: Do not use in dogs with central nervous system depression or seizures. Do not use in cases of ingestion of sharp foreign objects, corrosive agents (acids or alkalis), volatile substances or organic solvents. CLEVOR® should not be administered in cases with corneal ulceration, ocular irritation, or ocular injury. Do not use when there is a known sensitivity to ropinirole or the inactive ingredients. ADVERSE REACTIONS MAY INCLUDE: Transient mild or moderate hyperemia of the eye, ocular discharge, protrusion of the 3rd eyelid and blepharospasm, transient mild lethargy and increased heart rate. Not recommended for use in breeding, pregnant or lactating dogs. CLEVOR® has not been evaluated in dogs with heart or liver impairments or dogs younger than 4.5 months or less than 4 pounds. Dopamine antagonists, neuroleptics and other medicines with antiemetic properties may reduce the effectiveness of ropinirole. CLEVOR® should be administered by a veterinary professional. Gloves and protective eyewear should be worn when administering. Not for use in humans. Keep out of reach of children. For full prescribing information, visit www.vetoquinolusa.com/clevor-info.

References

  1. Suokko, M., Saloranta, L., Lamminen, T., Laine, T., Elliott, J. (2020) Ropinirole eye drops induce vomiting effectively in dogs: a randomised, double-blind, placebo-controlled clinical study. Veterinary Record, Mar 7;186(9):283.
  2. Clevor® (ropinirole ophthalmic solution) Prescribing Information. Orion Corporation.